Ebamine 5 mg/5 ml is used for the symptomatic treatment of:

• Seasonal and perennial allergic rhinitis
• Chronic idiopathic urticaria

Ebastine is a long-acting, selective H1-histamine receptor antagonist. With repeated use, it maintains consistent inhibition of peripheral H1 receptors. After oral administration, it is rapidly absorbed and undergoes extensive first-pass metabolism. Ebastine is almost completely converted into its active acid metabolite, carebastine.

Tablet:

• Adults (more than 12 years of age): 10 mg (one tablet) once daily.
• Children (6-12 years of age): 5 mg (half tablet) once daily.

Syrup:

• Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis).
• Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis).

Ebastine may be taken with or without food.

Patients with known hypersensitivity to ebastine or any of its components.

The most commonly reported side effects are headache, dry mouth, and drowsiness. Less frequently reported adverse effects include abdominal pain, dyspepsia, nausea, and insomnia.

No clinically significant signs or symptoms have been observed with doses up to 100 mg administered once daily. There is no specific antidote for ebastine. In the event of accidental overdose, gastric lavage, monitoring of vital signs including ECG, and appropriate symptomatic treatment are recommended.

Non-sedating antihistamines.

Store below 30°C in a cool, dry place, protected from light. Keep out of reach of children.