Polyethylene Glycol 3350 powder for oral solution is indicated for the treatment of occasional constipation in adults aged 18 years and above. It should be used for 2 weeks or less, or as directed by a physician.

Each bottle contains 85 g of Polyethylene Glycol 3350 USP NF powder for solution. The measuring cup provided with the bottle is used to measure 17 g or 8.5 g of powder.

The primary mechanism of action is the osmotic effect of polyethylene glycol 3350, which retains water in the colon and results in softer, watery stools. It induces bowel evacuation, usually within about four hours.

This is a white powder for reconstitution. It is a synthetic polyglycol with an average molecular weight of 3350. Polyethylene Glycol acts as an osmotic agent that retains water in the stool. It has no significant effect on the active absorption or secretion of glucose or electrolytes.

The usual dose of Polyethylene Glycol is 17 gm of powder per day (or as directed by physician) in a glass of water, juice, coke, coffee or tea. Each bottle of Polyethylene Glycol is supplied with a cup that is used to measure 17 gm or 8.5 gm of laxative powder when filled upto the marked line.

Information to the Patient: Polyethylene Glycol has been prescribed by physician to treat constipation. This product should only be used by the person for whom it is prescribed.

How to take: The dose of Polyethylene glycol is 17 gm each day or as directed by physician. It should always be taken by mouth. Measure the dose using the supplied cup, stir and dissolve in a glass of water, juice, coke, coffee or tea. Taking more than the prescribed dose may cause loss of fluid due to severe diarrhea.

How long should it be taken: Polyethylene glycol achieves its best results when used between one and two weeks. It may be discontinued after several satisfactory bowel movements. Should unusual cramps, bloating, or diarrhea occur, consultation with physician is needed. Polyethylene glycol is intended for up to a two-week course of therapy. It should not be used for a longer time unless directed by a physician. After successfully completing the Polyethylene glycol therapy (usually between one and two weeks) discussion with a physician is needed to change lifestyle that may produce more regular bowel habits (adequate dietary and fluid intake, regular exercise).

It should always be taken by mouth. Measure the dose using the supplied cup, stir and dissolve in a glass of water, juice, coke, coffee or tea. Taking more than the prescribed dose may cause loss of fluid due to severe diarrhea.

No specific drug interactions have been reported with Polyethylene Glycol.

Polyethylene Glycol is contraindicated in patients with known or suspected bowel obstruction and in patients with known hypersensitivity to polyethylene glycol.

Common side effects may include nausea, abdominal bloating, cramping, and flatulence. High doses may cause diarrhea and increased stool frequency, especially in elderly or nursing home patients. Rarely, allergic reactions such as urticaria have been reported in patients using polyethylene glycol-containing products.

It is not known whether Polyethylene Glycol causes harm to the fetus or affects reproductive capacity. It should be used during pregnancy only if clearly necessary. There is no sufficient information regarding its use during breastfeeding, so medical advice should be taken before use.

Patients with symptoms suggestive of bowel obstruction such as nausea, vomiting, abdominal pain, or abdominal distension should be evaluated before starting therapy. Polyethylene Glycol should be taken only after dissolving in water, juice, cola, coffee, or tea.

No accidental overdose cases have been reported. Overdose may mainly cause diarrhea. If excessive fluid intake is not maintained, dehydration may occur. Treatment includes stopping the drug and giving adequate fluids.

Osmotic purgatives

Store below 30°C, protect from light and moisture. Keep out of reach of children.