The combination of salicylic acid and sulfur is used for the treatment of: Acne and other skin disorders, Dandruff and other scalp conditions such as seborrheic dermatitis.

Salicylic acid is a potent keratolytic agent with mild antiseptic properties when applied topically. Sulfur is a scabicidal and keratolytic agent.

When used in combination, these two agents produce a synergistic keratolytic effect, enhancing the removal of dead skin cells. In acne treatment, salicylic acid may also contribute additional anti-inflammatory activity.

The dose of salicylic acid and sulfur will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of salicylic acid and sulfur. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acne or oily skin 

Bar dosage form:

• Adults and children: Use on the affected skin two or three times a day.

Cleansing lotion dosage form:

• Adults and children: Use on wet skin one to three times a day. Rub lather into skin for one minute then rinse.

For dandruff and seborrheic dermatitis of the scalp

Bar and shampoo dosage forms:

• Adults and children: Use on the scalp once a day at least two times a week or as directed by doctor. May be used each day if needed.

Use salicylic acid and sulfur only as directed. Do not use more of it and do not use it more often than recommended on the label, unless otherwise directed by your doctor. Immediately after using salicylic acid and sulfur, wash your hands to remove any medicine that may be on them. Keep salicylic acid and sulfur away from the eyes. If you should accidentally get some in your eyes, flush them thoroughly with water.

To use the skin cleansing lotion: After wetting the skin, apply salicylic acid and sulfur with your fingertips or a wet sponge and rub in gently to work up a lather. Then rinse thoroughly and pat dry.

To use the shampoo or bar as a shampoo: Wet the hair and scalp with lukewarm water. Then apply enough medicine to work up a lather and rub into the scalp. Continue rubbing the lather into the scalp for several minutes or allow it to remain on the scalp for about 5 minutes, depending on the product being used, then rinse. Apply the medicine again and rinse thoroughly.

To use the bar as a soap: After wetting the skin, use salicylic acid and sulfur to wash the face and other affected areas. Then rinse thoroughly and pat dry.

Certain medicines should not be taken at or around mealtime, as food interactions may occur. Alcohol or tobacco use may also interact with some medicines. Patients are advised to consult a healthcare professional regarding the use of this medicine with food, alcohol, or tobacco.

Hypersensitivity to the product or any of its components.

As with all medicines, this product may cause unwanted effects, although not everyone will experience them. Medical attention may be required if they occur.

Seek medical advice promptly if you experience skin irritation not present before use of salicylic acid and sulfur.

Some side effects may not require medical attention and may resolve as the body adjusts to the medicine. However, consult a healthcare professional if they persist or become bothersome, or if you have any concerns:

• Redness and peeling of the skin (may occur after a few days)
• Unusual dryness of the skin

Breastfeeding: Adequate studies are not available to determine infant risk during breastfeeding. The potential benefits should be weighed against possible risks before using this medication while breastfeeding.

When using the salicylic acid and sulfur combination, avoid applying the following products on the same affected area unless directed by a physician, as this may cause severe skin irritation:

• Abrasive soaps or cleansers
• Alcohol-containing preparations
• Other topical acne treatments or peeling agents (e.g., benzoyl peroxide, resorcinol, tretinoin [vitamin A acid])
• Drying cosmetics or soaps
• Medicated cosmetics
• Other topical skin medications

Do not use mercury-containing topical products (e.g., ammoniated mercury ointment) on the same area, as this may cause foul odor, skin irritation, and black discoloration of the skin. Consult a healthcare professional if needed.

Concurrent use of large doses of aspirin or other salicylates (including diflunisal) with topical salicylic acid may lead to salicylate toxicity. Consult your healthcare provider if you have any concerns.

Pediatric: Young children may absorb more salicylic acid through the skin, increasing the risk of side effects. Therefore, it should not be applied to large body areas or used for prolonged periods in infants and children.

Geriatric: Specific studies in elderly patients are limited. It is not known whether their response differs from younger adults. No specific age-related safety differences have been established for this combination.

Local antipruritic agents, other scalp preparations

Store in a tightly closed container at room temperature, away from heat, moisture, and direct light. Do not freeze. Keep out of reach of children. Do not use expired or no longer needed medicine.