Cholera Saline contains essential electrolytes that are commonly lost in conditions such as diarrhea, vomiting, and excessive sweating. Therefore, it is used in cholera, as well as in diarrhea, vomiting, and fluid loss, to restore and maintain the body’s normal electrolyte balance.

This is a sterile solution composed of Sodium Chloride, Potassium Chloride, and Sodium Acetate. Each 100 ml of the solution contains:

• Sodium Chloride BP 0.5 g
• Potassium Chloride BP 0.1 g
• Sodium Acetate BP 0.393 g

Per litre, the solution provides Sodium 134 mmol, Potassium 13 mmol, Chloride 99 mmol, and Acetate 48 mmol.

The volume and rate of infusion of Cholera Saline depends upon the requirements of the patient and the judgement of the physician. It usually varies with age, weight and clinical condition of the patient.

Administration

Administration Procedure:

• Check infusion set and infusion solution prior to use
• Pull moderately to tear off the protective cover of the Eurohead
• Hold lightly the Eurohead but not the bag
• Open the flow regulator fully and hold the giving set on the top white area, but not the membrane venting region
• Insert the spike of the administration set to the Eurohead and fit the connector of the administration set firmly to the needle
• Gradually allow the fluid to flow down to the needle tip and close
• Remove the protective cover of the needle
• Locate the venipuncture site and clean the site with an antiseptic solution, and then insert the needle
• Securely tape the puncture site
• Securely tape the wings and tubing
• Start infusion while adjusting drip speed

• Severe burning sensation, pain, or swelling at the IV injection site;
• Warmth, redness, discharge, or bleeding at the site of infusion;
• Fever or persistent cough.

As Cholera Saline contains multiple electrolytes, it should be administered cautiously in patients where electrolyte imbalance may pose risks, such as during pregnancy, renal impairment, heart failure, pulmonary congestion, head injury, or in those receiving potassium-sparing diuretics.

Intravenous fluid preparations

Store at controlled room temperature.