Cerebral circulatory disorders:

• Prophylaxis and maintenance therapy for symptoms related to cerebral vascular spasm and arteriosclerosis such as dizziness, tinnitus, vascular headache, irritability, fatigue, sleep disturbances (e.g., early awakening), depressive mood, memory impairment, reduced concentration, incontinence, and other age-related conditions
• Sequelae of cerebral and cranial injuries
• Post-stroke conditions
• Migraine

Peripheral circulatory disorders: Prophylaxis and maintenance therapy for symptoms of vascular spasm and arteriosclerosis (e.g., obliterative arteritis, thromboangiitis obliterans, Raynaud’s disease, diabetic vascular complications, acrocyanosis, etc.), including intermittent claudication, trophic disturbances, pregangrene, trophic and varicose ulcers, paraesthesia, nocturnal cramps, and cold extremities

Disorders of balance:

• Prophylaxis and maintenance therapy for labyrinthine and vestibular disorders such as Meniere’s syndrome presenting with vertigo, dizziness, giddiness, syncope, tinnitus, nystagmus, nausea, and vomiting
• Prevention of motion sickness
• Use medicines only as advised by a registered physician

This combination contains two active ingredients: cinnarizine and dimenhydrinate, belonging to different pharmacological classes. Cinnarizine is a calcium channel antagonist, while dimenhydrinate is an antihistamine. Both components act synergistically to reduce symptoms of vertigo (spinning sensation) and nausea. The combination has been found to be more effective than either agent used alone.

Adults: 1 tablet three times daily, to be taken after meals. Children and adolescents under the age of 18 years: Not recommended
Elderly: Dosage as for adults.

Concurrent use of alcohol, CNS depressants, or tricyclic antidepressants may enhance the sedative effects of cinnarizine and dimenhydrinate. Therefore, such combinations should be avoided.

This combination should not be used in patients with severe hepatic impairment or in those with known hypersensitivity to any of its components. It is also contraindicated in patients with angle-closure glaucoma, convulsive disorders, suspected increased intracranial pressure, alcohol abuse, or urinary retention due to urethroprostatic disorders.

Common adverse effects include drowsiness, dry mouth, headache, and abdominal discomfort. Rare side effects may include visual disturbances, allergic reactions, photosensitivity, and difficulty in urination. Other possible reactions include weight gain, constipation, chest tightness, jaundice, worsening of angle-closure glaucoma, involuntary movements, agitation, restlessness, and severe skin reactions.

This combination should not be used during pregnancy and breastfeeding.

Although it does not significantly lower blood pressure, caution is advised in hypotensive patients. The medication should be taken after meals to reduce gastric irritation. It should also be used cautiously in patients with Parkinson’s disease.

Overdose may cause drowsiness, dizziness, and ataxia along with anticholinergic effects such as dry mouth, facial flushing, dilated pupils, tachycardia, fever, headache, and urinary retention. Supportive treatment is recommended, and gastric lavage with isotonic sodium chloride solution may be considered.

Anti vertigo drugs

Store in a cool, dry place below 30°C, protected from light. Keep out of reach of children.