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Magaldrate + Simethicone

Generic Medicine
Indications

This combination is indicated to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux, and hiatal hernia. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis, and esophagitis. Magaldrate may be given to children if necessary. It is also indicated for the relief of flatulence, abdominal distension, and windy colic.

Pharmacology

This is a combination of magaldrate and simethicone. Magaldrate (magnesium aluminum compound, i.e., hydroxymagnesium aluminate) neutralizes gastric acid extraordinarily quickly without raising the pH above 5-6. It also decreases the activity of pepsin in gastric secretion. Besides this, simethicone, the other component, enables gas bubbles to coalesce and provides relief from flatulence.

Dosage Administration

Tablet: 1-4 chewable tablets, 20 to 60 minutes after meals and at bedtime, or as directed by the physician.

Suspension: 2-4 teaspoonfuls (10-20 ml) of suspension, 20 to 60 minutes after meals and at bed time, or as directed by the physician.

Interactions

It should not be used in patients taking any form of Tetracycline. The drug may cause reduced bioavailability or slower absorption of a number of drugs including propranolol, isoniazid, prednisolone, and naproxen.

Contraindications

Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminum. It is also contraindicated in patients with impaired renal function.

Side Effects

Gastrointestinal side effects are uncommon. Occasionally, if an excessive amount is consumed, diarrhea, constipation, or regurgitation may occur.

Pregnancy & Lactation

Magaldrate may be used in pregnancy if indicated; however, one should avoid excessive dosage. Magaldrate may pass into breast milk but has not been reported to cause problems in nursing babies.

Precautions & Warnings

Care should be taken in patients with decreased kidney function, hypophosphatemia, and weak or debilitated individuals.

Overdose Effects

Overdosage with this formulation is a rare occurrence.

Therapeutic Class

Antacids, Anti-dyspeptic/Carminatives

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Common Questions

What is Magaldrate + Simethicone for?

What does Magaldrate + Simethicone do?

What are the side effects of Magaldrate + Simethicone?

What happens if you take too much Magaldrate + Simethicone?

Can Magaldrate + Simethicone be taken during pregnancy?

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