This combination is indicated for the treatment of inflammation and infections of the external ear (otitis externa) as well as fungal infections of the outer ear (otomycosis).

Flumetasone Pivalate is a potent difluorinated glucocorticoid intended for topical use. It provides anti-inflammatory, anti-allergic, vasoconstrictive, and anti-proliferative effects. In inflammatory conditions of the external auditory canal, it offers rapid relief from symptoms such as itching and helps reduce swelling.

Clioquinol is a halogenated hydroxyquinoline derivative with bacteriostatic properties. It is effective against a wide range of microorganisms, including fungi (such as Candida, Microsporum, and Trichophyton) and Gram-positive bacteria (e.g., Staphylococci). It also shows activity against certain Gram-negative bacteria.

For adults and children (aged 2 years and over): The recommended dose is 2 to 3 drops twice daily for the prescribed period of time (usually not longer than 10 days). Before you apply the medication, you should warm the ear drops to body temperature by holding the bottle in the palm of your hands. Do not heat it above body temperature.

Topical use of clioquinol may increase protein-bound iodine (PBI) levels in patients with normal thyroid function, which can interfere with certain thyroid function tests such as PBI, radioactive iodine uptake, and butanol-extractable iodine tests. These tests should be avoided for at least one month after using this ear drop. Other tests like the T3 resin sponge test or T4 determination are not affected by clioquinol.

This medicine is contraindicated in patients with perforated eardrum, existing cutaneous tuberculosis, viral or fungal skin infections (such as chickenpox, herpes simplex, herpes zoster), or known hypersensitivity to corticosteroids, iodine, clioquinol, flumetasone pivalate, hydroxyquinolines, quinolone derivatives, or any component of this formulation.

Burning sensation, itching, and skin rashes may occur at the application site.

The safety of this medicine during pregnancy and breastfeeding has not been established.

Before starting treatment, the eardrum should be examined by a physician. If there is any risk of eardrum perforation, this ear drop should not be used. If no improvement is observed within one week, treatment should be discontinued. Identification of the causative organisms and appropriate therapy is recommended. Avoid contact of this ear drop with the eyes.

Application over large or damaged skin areas may increase PBI levels within one week. If symptoms resembling thyrotoxicosis appear, the medication should be discontinued immediately.

Aural steroid & antibiotic combined preparations, Ophthalmic steroid-antibiotic combined preparations

Keep out of reach of children. Store in a cool and dry place, protected from heat and direct light. Do not use for more than 4 weeks after opening.