This preparation is indicated for the treatment of symptoms caused by the reflux of acid, bile, and pepsin into the esophagus, such as acid regurgitation, heartburn, and indigestion—for example after gastric surgery, due to hiatus hernia, during pregnancy, and in association with reflux esophagitis. It is also used for symptoms of laryngopharyngeal reflux, including hoarseness, voice disorders, sore throat, and cough. Additionally, this preparation may be used to relieve gastroesophageal reflux symptoms during treatment with acid-suppressing therapy or after its withdrawal.

This preparation is a combination of Sodium Alginate and Potassium Bicarbonate. Sodium Alginate is a naturally occurring substance that reacts with stomach acid to form a gel-like layer. Potassium Bicarbonate reacts with gastric acid to produce carbon dioxide bubbles. These bubbles become trapped within the alginate gel, causing it to float on top of the stomach contents as a protective “raft.” This raft acts as a physical barrier that prevents stomach acid from flowing back into the esophagus, thereby relieving reflux symptoms such as heartburn. Its action is purely physical and does not depend on systemic absorption. The raft remains effective for up to 4 hours and is then broken down in the digestive system and eliminated in the feces.

Tablet:

• Adults and children over 12 years: 1-2 tablets 3-4 times daily, after meals and before bedtime.
• Children 6-12 years: ½-1 tablet 3-4 times daily, after meals and before bedtime.

Suspension:

• Adults and children 12 years and above: 5-10 ml (1-2 teaspoonfuls) 3-4 times daily, after meals and before bedtime.
• Children 2-12 years: 2.5-5 ml (½-1 teaspoonful) 3-4 times daily, after meals and before bedtime.

Use in children: This is not recommended under 2 years of age.

Elderly: No dose modifications are necessary for this age group.

Hepatic Impairment: No dose modifications are necessary.

Renal Insufficiency: Caution if a highly restricted salt diet is necessary.

A time interval of at least 2 hours should be maintained between this medicine and other medicinal products, especially tetracyclines, fluoroquinolones, iron salts, thyroid hormones, chloroquine, bisphosphonates, and estramustine.

Sodium Alginate and Potassium Bicarbonate are contraindicated in patients with known hypersensitivity to these ingredients.

Besides the desired effect, some side effects may occur such as nausea, constipation, diarrhea, or headache. In such cases, medical advice should be taken. In case of excessive dose, a feeling of abdominal bloating or swelling may occur, and consultation with a physician is recommended.

This combination of Sodium Alginate and Potassium Bicarbonate may be used during pregnancy if clinically necessary. No harmful effects are known in breastfed infants, and it can be used during breastfeeding.

Sodium Alginate and Potassium Bicarbonate should be used with caution in patients with renal impairment and congestive heart failure. Care is needed in patients with hypercalcemia, nephrocalcinosis, or recurrent calcium-containing kidney stones. Efficacy may be reduced in patients with very low gastric acid levels. If symptoms do not improve within 7 days, the condition should be reassessed.

Overdose is rare with this formulation. In case of suspected overdose, consult a registered physician immediately.

Antacids

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.