Sodium Chloride Tablets is indicated for the treatment and prevention (prophylaxis) of sodium chloride deficiency.

Sodium chloride is the principal salt responsible for maintaining the osmotic pressure of blood and body tissues. Changes in osmotic balance influence fluid movement and salt diffusion in cells. Sodium Chloride Tablets provides a source of sodium in cases of deficiency. Sodium chloride is readily absorbed from the gastrointestinal tract and is present in all body fluids, especially extracellular fluid. Normal sodium loss through sweat is minimal. Osmotic balance is maintained by excretion of excess sodium through urine.

It is important that the tablet should be swallowed whole with water (approx. 70 ml per tablet where kidney function is normal to avoid hypernatremia), and not chewed.

Adults: For prophylaxis 8-16 tablets per day. For treatment dosage to be adjusted to individual needs up to a maximum of 40 tablets per day in case of severe salt depletion. For control of muscle cramps during routine maintenance haemodialysis usually 20-32 tablets per dialysis. In some cases of chronic renal salt-wasting, up to 40 tablets per day may be required with appropriate fluid intake.

Children: Dosage should be adjusted to individual needs.

Elderly: No special dosage adjustment.

In hypertensive patients with chronic renal failure, Sodium Chloride 300 mg Tablets may reduce the effectiveness of antihypertensive drugs.

Sodium Chloride 300 mg Tablets is contraindicated in any condition where sodium retention is undesirable, such as edema, heart disease, cardiac decompensation, and primary or secondary aldosteronism. It is also contraindicated where therapy is intended to promote salt and water loss.

No side effects have been reported with Sodium Chloride 300 mg Tablets at the recommended dose.

No special precautions are required during pregnancy. Sodium Chloride 300 mg Tablets can be used when needed.

No special warnings or precautions are required.

Signs & Symptoms: Excess intake of sodium chloride may lead to hypernatremia. Symptoms include restlessness, weakness, thirst, reduced saliva and tears, swollen tongue, skin flushing, fever, dizziness, headache, reduced urine output, high blood pressure, fast heartbeat, delirium, rapid breathing, and respiratory arrest.

Treatment: Management includes sodium-free fluids and stopping excess sodium intake. Serum sodium levels should be checked immediately. In severe cases, loop diuretics (e.g., frusemide) with potassium supplementation may be required. Monitoring should continue until levels normalize.

Oral electrolyte preparations

Store below 30°C in a dry place, protected from light. Keep out of reach of children.