Diclofenac Sodium ophthalmic preparation is indicated in:

• Pre- and post-operative cover (e.g., cataract surgery)
• Non-infected chronic conjunctivitis and keratoconjunctivitis
• Non-infected post-traumatic conditions of the cornea and conjunctiva

Diclofenac Sodium works by blocking the action of cyclo-oxygenase (COX) enzymes. Cyclo-oxygenase is involved in the production of various chemical substances in the body, including prostaglandins. Prostaglandins are released in response to injury or certain diseases and are responsible for causing pain, swelling, and inflammation. By inhibiting their production, diclofenac reduces these symptoms.

Pre-operatively: Instill 1 drop in the conjunctival sac up to 5 times over the 3 hours preceding surgery.

Post-operatively: Instill 1 drop in the conjunctival sac after 15, 30 & 45 minutes following surgery; then 3–5 times daily for as long as required.

Inflammatory conditions: Instill 1 drop in the conjunctival sac 4–5 times daily depending upon the severity of the disease.

No significant drug interaction has been reported. There should be at least a 5-minute interval when another ophthalmic solution (e.g., steroid eye drops) is administered.

Diclofenac Sodium eye drops are contraindicated in patients with hypersensitivity to any of its components. Like other non-steroidal anti-inflammatory drugs, it is contraindicated in patients who develop asthma, urticaria, or acute rhinitis after using acetylsalicylic acid or other cyclo-oxygenase (COX) inhibitors.

Mild to moderate burning sensation occurs in 5–15% of patients, which is usually temporary and rarely requires discontinuation of treatment. Other less common side effects include: Sensitivity to light, Bad taste, Feeling of pressure in the eye, Allergic reactions.

The safety of Diclofenac eye drops during pregnancy and lactation has not been established. Therefore, its use is not recommended unless the potential benefit to the mother outweighs the possible risk to the child.

Diclofenac eye drops may mask signs of infection. Therefore, physicians should monitor for any development of infection during treatment. During prolonged use, regular eye examinations are recommended, including measurement of intraocular pressure. Contact lenses should not be worn during treatment.

Ophthalmic non-steroidal anti-inflammatory drugs (NSAIDs)

Close the bottle immediately after use. Do not use for more than four weeks after opening. Store at room temperature.