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Chaste berry

Generic Medicine
Indications

Chaste berry 20 mg capsule is indicated for the treatment and prevention of irregular menstruation, premenstrual syndrome (PMS) including lower abdominal pain, sleep disturbance, cyclical mastalgia, acne, headache, and mood swings, as well as hyperprolactinemia and mastodynia.

Pharmacology

Chaste berry (Vitex agnus-castus) is native to Western Asia and Southwestern Europe. It is widely used in gynecological conditions due to its dopaminergic activity at the central level. It has been traditionally used in Europe for premenstrual syndrome, menstrual irregularities, cyclical breast pain, and dysfunctional uterine bleeding.

Its major active compounds include iridoid glycosides such as agnuside and aucubin, along with flavonoids like casticin. It acts as a hormonal modulator by influencing progesterone levels and reducing prolactin secretion through pituitary dopamine receptor activity. It also affects FSH and LH regulation, contributing to hormonal balance.

Dosage Administration

Orally 1-2 capsules daily with water or as advised by the physician. Duration of the treatment should be at least 3 months and a repeated course is feasible as advised by the physician.

Contraindications

Contraindicated in individuals with known hypersensitivity to chaste berry.

Side Effects

Generally well tolerated at recommended doses. Rare side effects (1–2%) may include nausea, rash, headache, hair loss, fatigue, agitation, dry mouth, tachycardia, and increased menstrual flow.

Pregnancy & Lactation

Not recommended during pregnancy. No restriction has been reported during lactation.

Therapeutic Class

Herbal and nutraceutical preparations.

Storage Conditions

Do not store above 30°C. Protect from light and moisture. Keep out of reach of children.

Common Questions

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No available drugs found

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