Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma and lumbago.

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) with both pain-relieving (analgesic) and anti-inflammatory effects. It works by inhibiting the cyclooxygenase (COX) enzyme, which plays a key role in the production of prostaglandins—substances responsible for pain, inflammation, and swelling.After oral administration, Aceclofenac is rapidly and almost completely absorbed in the body in its unchanged form, ensuring effective action.

Extended release tablet: The recommended dose in adults is one 200 mg Aceclofenac tablet daily or as prescribed by the physician.

Film coated tablet: The recommended dose in adults is 100 mg, twice daily.

No significant drug interactions have been observed, but close monitoring of patients is required when it is used with:

• Lithium and Digoxin: May increase plasma concentration of lithium and digoxin.

• Diuretics: May interact with the activity of diuretics.

• Anticoagulants: May enhance the activity of anticoagulants.

• Methotrexate: May increase the plasma level of methotrexate.

Aceclofenac is contraindicated in patients with known hypersensitivity to it or in whom aspirin or NSAIDs precipitate attacks of asthma.

(Note: The original text repeated the pharmacology section here. Common side effects of Aceclofenac include gastrointestinal disturbances such as nausea, vomiting, diarrhea, abdominal pain, dyspepsia, as well as dizziness, headache, and rash.)

Aceclofenac should generally be avoided during pregnancy and breastfeeding unless the potential benefit outweighs the possible risks to the fetus or infant. Always consult a doctor before use.

Caution should be exercised in patients with active or suspected peptic ulcer or gastrointestinal bleeding, moderate to severe hepatic impairment, and cardiac or renal impairment. Caution should also be exercised in patients suffering from dizziness or vertigo.

There are no clinical data on the use of Aceclofenac in children.

Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-Inflammatory Drugs (NSAIDs)

Keep in a dry place away from light and heat. Keep out of the reach of children.