This preparation is indicated for: Relief of cough and associated congestive symptoms .Relief of: Runny nose, Sneezing, Watery eyes, Itchy nose, eyes, and throat, Other allergic symptoms.

Diphenhydramine possesses antitussive (cough-suppressing) and antihistaminic properties. It relieves cough by acting centrally (on the brain stem). It treats sneezing, runny nose, and allergic symptoms such as itchy eyes, nose, and skin. Levomenthol has decongestant and anti-inflammatory properties. It helps soothe cough. It reduces congestion and inflammation in the nasal passages and lungs, making breathing easier.

Adults and Children over 12 years: The recommended dose is 10 ml of syrup 4 times a day. Maximum daily dose is 40 ml syrup.

Diphenhydramine may potentiate (enhance) the effects of: Alcohol, Codeine , Other CNS depressants, Anticholinergics (e.g., some psychotropic drugs and atropine) and Other antihistamines .MAO inhibitors potentiate and intensify the anticholinergic effects of antihistamines.

This preparation is contraindicated in: Individuals with known hypersensitivity to the product or any of its constituents. Individuals with chronic or persistent cough, such as occurs with asthma, or where cough is accompanied by excessive secretions, unless directed by the physician. Patients currently receiving monoamine oxidase inhibitors (MAOIs) , or those who have received treatment with MAOIs within the last two weeks.

Diphenhydramine may cause: Drowsiness, Dizziness, Gastrointestinal disturbance, Dry mouth, nose, or throat, Difficulty in urination, Blurred vision.

Diphenhydramine has been in widespread use for many years without ill consequence. However, it is known to cross the placenta and has been detected in breast milk. Therefore, it is only used when the potential benefit of treatment to the mother exceeds any possible hazards to the developing fetus or suckling infant.

This preparation may cause drowsiness. Caution should be exercised in patients with moderate to severe renal or hepatic dysfunction or urinary retention when using this preparation. Diphenhydramine should not be taken by individuals with: Narrow-angle glaucoma, Symptomatic prostatic hypertrophy (enlarged prostate).

Signs and symptoms of overdose may include: Drowsiness, Hyperpyrexia (very high fever), Anticholinergic effects With higher doses, CNS excitation, including hallucinations and coma, or cardiovascular collapse, may appear. Management: Treatment of overdose should be symptomatic and supportive. Rapid gastric emptying (with Syrup of Ipecac-induced emesis or gastric lavage) and activated charcoal may be useful. Seizures may be controlled with Diazepam or Thiopental Sodium. Physostigmine IV may be efficacious to antagonize severe anticholinergic symptoms.

Combined cough expectorants

Keep below 30°C. Protect from light and moisture. Keep out of the reach of children.