Tiemonium Methylsulfate is an antispasmodic medication that helps relax muscle spasms in the intestine, biliary system, bladder, and uterus. It is used to relieve pain caused by functional disorders of the digestive tract and biliary system. Additionally, it is indicated for managing spasm and pain associated with urological and gynecological conditions.

Tiemonium Methylsulfate acts as a competitive antagonist of acetylcholine and histamine. It also enhances calcium binding with membrane phospholipids and proteins, which inhibits the contraction of visceral smooth muscles. This action reduces muscle spasms and alleviates pain in affected organs.

Tablet/Syrup-

• Adult: usual dose is 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses.
• Children: 3 ml/kg or 6 mg/kg body weight daily in divided doses.

Injection: 1 injection 3 times daily, through Intravenous route slowly or Intramuscular route.

Suppository: 20 mg suppository two or three times daily, through rectal route.

Tiemonium Methylsulphate tablets should not be taken with other medications without consulting a registered physician to prevent possible drug interactions.

This medicine should not be used in patients with urethroprostatic disorders that may cause urinary retention. It is also contraindicated in individuals at risk of angle-closure glaucoma.

Some patients may experience low blood pressure (hypotension) or rapid heart rate (tachycardia) while using Tiemonium Methylsulphate.

Animal studies have not shown any teratogenic effects of Tiemonium Methylsulphate, and no deformities have been reported with normal use. In the absence of sufficient human data, caution is advised for nursing mothers, although no problems have been reported with standard use.

Caution is advised when treating patients with prostate disorders. Extra care should be taken in individuals with chronic bronchitis, coronary insufficiency, high environmental temperature, or kidney and liver problems. Visual disturbances may occur, which can make driving or operating machinery hazardous.

Paediatric use: The safety and effectiveness of Tiemonium Methylsulphate in children have not been established.
Geriatric use: The efficacy and safety of Tiemonium Methylsulphate are maintained in elderly patients.

There is no available data regarding overdose of Tiemonium Methylsulphate tablets.

Store in a dry place, protected from light and heat. Keep out of reach of children.

Anticholinergics