Aluminium Hydroxide and Magnesium Hydroxide are indicated for the relief of hyperacidity, peptic ulcer, gastritis, heartburn, acid indigestion, and dyspepsia.
Aluminium Hydroxide + Magnesium Hydroxide
Generic MedicineComposition
Each tablet contains:
- Dried Aluminium Hydroxide Gel BP (minimum 47% Al₂O₃): 250 mg
- Magnesium Hydroxide BP: 400 mg
Each 5 ml contains:
- Aluminium Oxide (equivalent to Aluminium Hydroxide Gel USP): 175 mg
- Magnesium Hydroxide (equivalent to Magnesium Hydroxide Paste USP): 225 mg
Pharmacology
This preparation is a balanced combination of non-systemic antacids known for their effectiveness and good tolerability. It provides reliable acid neutralization without causing acid rebound or significant constipating or laxative effects. Both components help relieve symptoms of hyperacidity such as heartburn, acid indigestion, and sour stomach.
Aluminium hydroxide gel acts as a slow-acting antacid with prolonged duration and strong acid-neutralizing capacity. Magnesium hydroxide also neutralizes acid gradually but maintains a sustained effect. Both tablet and suspension forms possess adsorptive properties, forming a protective layer over ulcerated areas, which promotes healing and protects the gastric and duodenal mucosa from further irritation.
Dosage Administration
Tablet: Two tablets 1–3 hours after meal and at bed time or as directed by the physician.
Suspension: 2 tea spoonful 1–3 hours after meal and at bed time or as directed by the physician.
Interactions
This preparation may reduce the absorption of several medications, including: Azithromycin, cefpodoxime, ciprofloxacin, isoniazid, rifampicin, norfloxacin, ofloxacin, pivampicillin, tetracyclines, gabapentin, phenytoin, itraconazole, ketoconazole, chloroquine, hydroxychloroquine, and phenothiazines.
Contraindications
This preparation is contraindicated in patients with hypophosphataemia. It should also be avoided in conditions such as alkalosis and hypermagnesaemia, particularly when abdominal distension may be associated with partial or complete intestinal obstruction.
Side Effects
Prolonged use of antacids may lead to alkaluria, which can increase the risk of kidney stone formation due to calcium phosphate deposition.
Pregnancy & Lactation
Use of antacid preparations should preferably be avoided during the first trimester of pregnancy.
Precautions & Warnings
Antacids can reduce the absorption of tetracycline when used together. Therefore, concurrent administration should be avoided.
Therapeutic Class
Antacid preparations.
Storage Conditions
Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.
Common Questions
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