Amorolfine Hydrochloride (Nail Lacquer) is indicated for the treatment of onychomycosis (fungal nail infections) caused by dermatophytes, yeasts, and moulds.

Amorolfine is a topical antifungal agent belonging to the morpholine class. It exerts either fungistatic or fungicidal effects by disrupting the fungal cell membrane, mainly through interference with sterol biosynthesis. It has a broad spectrum of activity and is effective against yeasts, dermatophytes, moulds, Dematiaceae, and dimorphic fungi.

Amorolfine Nail Lacquer should be applied to the affected finger or toenails once or twice a week as directed by the doctor It is important to use Amorolfine until the infection has cleared and healthy nails have grown back usually takes 6 months for fingernails and 9 to 12 months for toenails.

Administration

Step 1: File the nail: First file down the infected areas of nail including the nail surface, as much as possible using the nail file provided. Do not use this all file on healthy nails, otherwise the infection will be spread out Discard the nail file after use.

Step 2: Clean the nail: Use one of the alcohol pads provided to clean the nail surface. Repeat steps 1 and 2 for each affected nail.

Step 3: Take some lacquer from the bottle: Use a nail brush to apply the nail lacquer. The lacquer must not be wiped off the edge of the bottle before it is applied. Do not use the brush on healthy nails and wash the brush with hot water after use

Step 4: Apply the lacquer: Apply the lacquer evenly over the entire surface of the nail. Repeat these steps for each affected nail. Let the treated nail(s) dry for approximately 3 minutes. Close the nail lacquer bottle tightly. Dispose of the alcohol pad.

• Before using the nail lacquer again, first remove the old lacquer from your nails using a swab, then file down the nails again if necessary.
• Re-apply the lacquer as previously described  বাংলায় দেখুন
• When dry, the nail lacquer is unaffected by soap and water. So you may wash your hands and feet as normal.

No clinically significant drug interactions have been reported with Amorolfine Hydrochloride (Nail Lacquer).

This product should not be used in individuals with known hypersensitivity to Amorolfine or any of its components.

Side effects are uncommon and usually mild:

• Rare (less than 1 in 1000): Nail discoloration, brittleness, or damage
• Very rare (less than 1 in 10000): Burning sensation or allergic skin reaction (contact dermatitis)
• Frequency unknown: Redness, itching, hives, blisters, or allergic skin reactions

There is limited information regarding the use of Amorolfine in pregnant or breastfeeding women. It is not known whether the drug passes into breast milk. Use only if clearly necessary and advised by a healthcare professional.

Avoid contact of the lacquer with eyes, ears, and mucous membranes (such as mouth and nostrils). Do not inhale the product. When using organic solvents, wear protective gloves to prevent removal of the lacquer layer.

No information is available regarding overdose in humans.

Other topical preparations.

Store below 30°C. Protect from heat and keep the bottle tightly closed when not in use.