Higher concentrations of Benzalkonium chloride are used as an antiseptic and disinfectant. It is also widely utilized as a preservative in ophthalmic preparations such as eye drops.

Benzalkonium chloride is a quaternary ammonium compound with antiseptic and disinfectant properties. It is commonly used as an antimicrobial preservative in pharmaceutical formulations. It is also effective in disinfecting rigid contact lenses.

• Tincture of benzalkonium chloride 1:750 is used for the preoperative disinfection of unbroken skin or treatment of superficial injuries.
• For preoperative disinfection of mucous membranes and denuded skin, benzalkonium chloride solution in concentrations of 1:10000 to 1:2000 is used.
• For irrigation of the eye, a solution of 1:10000 to 1:5000 is used.
• For urinary bladder and urethral irrigation, a solution 1:5000 to 1:20000 is used.
• For vaginal douche and irrigation, benzalkonium chloride solution 1:5000 to 1:20000.

Disinfectants containing quaternary ammonium compounds should not be used for skin preparation prior to injection of viscoelastic substances, as they may cause precipitation of hyaluronic acid.

Benzalkonium chloride is incompatible with soaps and other anionic surfactants, as well as with substances such as citrates, iodides, nitrates, permanganates, salicylates, silver salts, tartrates, and zinc oxide or sulfate.

Repeated use may lead to hypersensitivity reactions. Accidental ingestion may cause nausea and vomiting.

Bleaching and disinfecting agents.

Store below 30°C, protected from light and moisture. Keep out of reach of children.