This combination is indicated in

• vaginal trichomoniasis,
• vaginal leucorrhoea,
• and mixed vaginal infections (fungal or bacterial).

Each vaginal suppository contains:

• Metronidazole BP 200 mg
• Neomycin Sulphate BP 35,000 IU
• Polymyxin B Sulphate BP 35,000 IU
• Nystatin BP 100,000 IU

Metronidazole, a nitroimidazole, is active against various anaerobic bacteria and protozoa. Nystatin is a polyene antifungal antibiotic. Neomycin is an aminoglycoside antibiotic, bactericidal and effective against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms, including Pseudomonas aeruginosa.

One suppository in the vagina at bedtime for 12 days or as directed by the physician.

Contraindicated in patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate, and Nystatin.

Skin rash and urticaria may occur rarely.

Caution should be practiced in pregnancy and lactation.

Caution should be taken in case of renal impairment.

Drugs used in vaginal and vulval conditions.

Store in a cool and dry place, away from light & children.