For the topical treatment of inflamed dermatoses where infection by susceptible organisms and inflammation coexist e.g. intertrigo and infected eczema. For moist or dry eczema or dermatitis including atopic eczema, primary irritant or contact allergic eczema or seborrheic eczema including that associated with acne. Also for intertriginous eczema including inflammatory intertrigo, perianal and genital dermatitis. Organisms which are susceptible to miconazole are dermatophytes and pathogenic yeasts (e.g. Candida spp.): also many Gram-positive bacteria including many strains of Streptococcus and Staphylococcus.

Miconazole is a substituted imidazole, is one of the family of azoles useful in treating superficial candidiasis and skin infections such as dermatophytosis and pityriasis versicolor, acanthameba, seborrhoeic dermatitis. It is also active against Aspergillus spp., Cryptococcus neoformans, Pseudallescheria boydii and some gram-positive bacteria including Staphylococci and Streptococci.

Hydrocortisone is a naturally occurring glucocorticoid now prepared synthetically. Its important function is in skin injury such as inflammation. It also has antipruritic, antimycotic and vasoconstrictive activity.

Miconazole is an imidazole antifungal agent that interferes with ergosterol synthesis and alters the permeability of the cell membrane of sensitive fungi, leading to fungal cell death. When applied to the skin, Hydrocortisone is absorbed into skin cells and prevents the release of certain chemicals responsible for inflammation, thus reducing inflammation.

Apply to the affected area as a thin film two or four times daily for 1 to 2 weeks. Rub it well with your finger until this cream fully vanished on the skin. Treatment should be continued at least one week after the disappearance of all signs and symptoms. The same dosage applies to both adults and children.

Amphotericin antagonizes the activity of Miconazole.

It is contraindicated in individuals who are hypersensitive to it or any of its components. Should not be used in pregnant and lactating mothers without physician’s advice.

Rarely local sensitivity may occur. Long term use may decrease the production of natural hormones by the adrenal gland.

Administration of corticosteroids to pregnant animal at high doses can cause abnormalities of fetal development. Topical steroids should not be extensively used in pregnancy.

To be dispensed only on the prescription of a registered physician. Keep out of reach of children. Take care or consult with a physician in case of use in children and elderly people for long-term use.

Hydrocortisone & Combined preparations

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.