Minoxidil topical solution is indicated for the treatment of:

• Male androgenetic alopecia (male pattern hair loss) on the top of the scalp (vertex).
• Female androgenetic alopecia (female pattern hair loss) on the top of the scalp.

Minoxidil topical solution has been shown to stimulate hair growth in males with androgenetic alopecia. The basic change in androgenetic alopecia is the conversion of terminal, non-vellus hair to vellus hair, i.e., hair which is thinner, shorter, and less pigmented.

Although the exact mechanism of action of Minoxidil in the treatment of androgenetic alopecia is not known, there may be more than one mechanism by which Minoxidil topical solution stimulates hair growth; these include:

• vasodilation of the microcirculation around the hair follicles, which may stimulate hair growth;
• direct stimulation of hair follicle cells to enter a proliferative phase;
• resting phase (telogen) follicles being stimulated to enter the growth phase (anagen).

Minoxidil 2% Solution: A total dose of 1 mL (7 sprays) Minoxidil topical 2% solution (20 mg Minoxidil) should be applied twice per day to the scalp, beginning at the center of the affected area. This dose should be used regardless of the size of the affected area. The total daily dose should not exceed 2 mL (40 mg Minoxidil). Suitable for men and women use.

Minoxidil Topical 5% Solution: Apply 1 mL (7 sprays) 2 times a day directly onto the scalp in the hair loss area. It should be used for men only.

Minoxidil topical solution should not be used along with other topical agents known to alter the stratum corneum barrier such as tretinoin or dithranol, due to the enhanced absorption of Minoxidil. Although there is no clinical evidence, there exists a theoretical possibility that absorbed Minoxidil may potentiate orthostatic hypotension caused by peripheral vasodilators.

• History of sensitivity to Minoxidil
• Treated or untreated hypertension
• Scalp abnormality (including psoriasis and sunburn)
• Shaved scalp
• Occlusive dressings or other topical medical preparations are being used

• Colds and respiratory infections
• Rhinitis
• Sinusitis
• Coughing
• Scaling
• Itching
• Rash

Systemically absorbed Minoxidil is secreted in human milk. There are no adequate and well-controlled studies in pregnant women. Animal studies have shown a risk to the fetus at exposure levels that are very high compared to those intended for human exposure.

Minoxidil topical solution is for external use only. Apply only to the scalp. Before applying this solution, the user should ensure that the scalp is normal and healthy. Hands should be washed thoroughly after use. Inhalation of the spray should be avoided. This solution contains ethanol (alcohol), which may cause burning and irritation of the eye. In case of accidental contact with sensitive surfaces (eye, abraded skin, mucous membranes), the area should be washed with large amounts of cool tap water.

Other scalp preparations

Do not store above 30°C. Keep away from light and moisture. Keep out of reach of children.