This combination topical gel is indicated for mild to moderate anti-inflammatory and analgesic use, providing symptomatic relief of muscular pain, stiffness, sprains, strains, and pain associated with rheumatic and non-serious arthritic conditions.

The combination of Mucopolysaccharide Polysulphate (MPS) and Salicylic Acid is a topical preparation used for anti-inflammatory and analgesic effects in mild to moderate musculoskeletal conditions. MPS is a non-steroidal agent with anti-inflammatory properties, showing a weak inhibition of prostaglandin E2 (PGE2) synthesis and an indirect effect on leukotriene B4 (LTB4) production in in vitro studies. It also exhibits anticoagulant, thrombolytic (via potentiation of urokinase activity), and anti-exudative effects through inhibition of hyaluronidase. Salicylic acid is a non-steroidal anti-inflammatory agent with keratolytic, analgesic, and anti-inflammatory properties. It softens the skin, enhancing penetration of MPS into underlying inflamed tissues. The gel formulation allows easy topical application and massage, helping relieve pain and inflammation locally. The effects of Mucopolysaccharide Polysulphate and Salicylic Acid are strictly local.

Adults, the elderly and children over 12 years of age: Two to six inches (5-15 cm) to be massaged to the affected area up to four times a day.

Use in Childhood and Adolescence: Should not be used on children below 12 years old.

Drugs or herbal products that may reduce the effectiveness of hormonal contraceptives (HCs) include efavirenz, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, rifabutin, rufinamide, and aprepitant. Such interactions may lead to breakthrough bleeding or contraceptive failure. There is also a risk of increased serum potassium levels when used with drugs such as ACE inhibitors, angiotensin II receptor antagonists, potassium-sparing diuretics, potassium supplements, heparin, aldosterone antagonists, and NSAIDs.

Hypersensitivity to any ingredient, aspirin, or other non-steroidal anti-inflammatory drugs (NSAIDs), especially in patients with a history of asthma. Should not be applied to large areas of skin, broken, sensitive or infected skin, eczema, or mucous membranes. Not recommended for children under 12 years of age. Avoid use during the first trimester, late pregnancy, or on the breast area during lactation.

Like all medicines, this gel may cause side effects in some individuals. Rarely, redness, burning sensation, or skin rash may occur. If any of these happen, discontinue use and consult a doctor.

If you are pregnant, breastfeeding, think you may be pregnant, or planning pregnancy, consult a doctor before use. The gel should not be used during the first or last three months of pregnancy or on the breast area during breastfeeding.

For external use only. Avoid contact with eyes. Do not exceed the recommended dose. If symptoms persist or worsen, consult a doctor or pharmacist. Salicylate-related side effects are theoretically possible. Consult a doctor before use if pregnant, breastfeeding, asthmatic, have kidney problems, or are taking other prescribed medicines (including anticoagulants). Salicylic acid may increase skin absorption of other topical medicines. Some users may experience discomfort, especially those with sensitive skin or when used in hot weather or after bathing. Wash hands after use. Discontinue if severe irritation occurs.

Store below 30°C, protected from light and moisture. Keep out of reach of children.