This combination cream is indicated for the treatment of corticosteroid-responsive dermatoses that are complicated by bacterial and fungal infections. It is also effective in managing conditions such as tinea pedis, tinea cruris, tinea corporis, as well as acute and chronic eczema.

Each gram of cream contains:

• Betamethasone Dipropionate USP 0.64 mg (equivalent to Betamethasone 0.5 mg)
• Clotrimazole USP 10 mg
• Gentamicin Sulfate USP 1.693 mg (equivalent to Gentamicin 1 mg)

This cream combines the anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone dipropionate with the broad-spectrum antifungal activity of clotrimazole and the bactericidal action of gentamicin sulfate. Clotrimazole disrupts fungal cell membranes, leading to leakage of cellular contents and fungal cell death. Gentamicin provides effective treatment against a wide range of bacteria responsible for primary and secondary skin infections.

Apply gently into the affected skin areas twice daily. Duration of therapy varies depending upon the extent and location of disease and patient response. For effective treatment, This Cream should be applied regularly.

Use in children: The safety and effectiveness of this preparation has not been established in children.

Concurrent use with nephrotoxic drugs such as other aminoglycosides, vancomycin, and certain cephalosporins, or with ototoxic agents like ethacrynic acid and furosemide, may increase the risk of toxicity.

This cream is contraindicated in patients with known hypersensitivity to any of its components.

Adverse effects are rare but may include hypopigmentation, burning sensation, redness, and oozing from the affected area.

The safety of topical corticosteroids in pregnancy has not been fully established. This preparation should be used during pregnancy only if the potential benefit justifies the possible risk to the fetus. Caution is advised when used in breastfeeding mothers.

Avoid using this product in combination with other corticosteroid-containing preparations. It should not be applied to the face and contact with the eyes must be avoided. Do not use for prolonged periods, over large areas, under occlusive dressings, or on open wounds, damaged skin, external genital areas, or skin folds.

Betamethasone & combined preparations.