Dexpanthenol ointment is indicated for:

• Prevention and treatment of diaper rash in infants.
• Prevention and treatment of cracked or sore nipples in breastfeeding women.
• Prevention and treatment of chafed, cracked, or split skin.
• Treatment of minor skin wounds and dry skin.

Pantothenic acid is essential for normal epithelial function. Dexpanthenol, a stable alcohol analogue of pantothenic acid, is used topically due to its good skin penetration and the ability to achieve high local concentrations when delivered in suitable formulations such as water-in-oil emulsions. Topical dexpanthenol acts as a moisturizer by improving hydration of the stratum corneum, reducing transepidermal water loss, and maintaining skin softness and elasticity.

Dexpanthenol is an alcohol derivative of pantothenic acid, which is a component of the vitamin B complex and an essential factor for normal epithelial function. It is enzymatically converted into pantothenic acid, a key component of Coenzyme A, which acts as a cofactor in many enzymatic reactions involved in epithelial protein metabolism.

Topical use of dexpanthenol produces dermatological effects such as increased fibroblast proliferation and faster re-epithelialization during wound healing. In addition, it acts as a skin protectant and moisturizer and has shown anti-inflammatory properties.

Check with the doctor or pharmacist if you are unsure how to use Dexpanthenol.

The usual dosage is generally:

• Diaper rash: Apply a thin layer on the baby’s bottom at every diaper change.
• Nipples: Apply a thin layer on the nipples after each nursing session. Wash the nipples thoroughly before the next nursing session.
• Dry/cracked skin or light wounds and chafed skin: Apply to the dry areas and/or to the wound up to 3 times a day.

Do not exceed the recommended dose, Do not swallow. This medicine is intended for external use only.

As with all medicines, Dexpanthenol may cause side effects in some users. Do not be alarmed by the list of possible side effects, as you may not experience any of them. Stop using the product and seek medical advice immediately if you develop an allergic reaction or skin reactions such as atopic dermatitis, allergic dermatitis, itching (pruritus), redness, rash, eczema, urticaria, local irritation, or blistering. If any side effect occurs, worsens, or if you notice any reaction not mentioned in this leaflet, consult a doctor.

Miscellaneous topical agents

Store below 30°C. Protect from light and keep out of reach of children.