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Riboflavin

Generic Medicine
Indications

For prevention and treatment of vitamin B2 (riboflavin) deficiency conditions such as cheilosis, angular stomatitis, glossitis, keratitis, and seborrhoeic dermatitis.

Pharmacology

Riboflavin (Vitamin B2) is a water-soluble, easily absorbed micronutrient essential for maintaining normal human health. It plays a key role in energy production by assisting the metabolism of carbohydrates, fats, and proteins. It is also necessary for red blood cell formation, cellular respiration, antibody production, and regulation of growth and reproductive functions. Additionally, riboflavin supports healthy skin, hair, nails, and overall well-being, including thyroid regulation. It is also involved in maintaining eye health and may help in preventing or managing certain eye disorders, including cataracts.

Riboflavin acts as a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). It interacts with riboflavin-dependent enzymes such as riboflavin kinase and riboflavin synthase. Its antioxidant activity is mainly due to its conversion into FAD, which plays a crucial role in the production of reduced glutathione. Reduced glutathione is an important antioxidant involved in cellular defense and is regenerated by the FAD-dependent enzyme glutathione reductase.

Dosage Administration

For treating low levels of riboflavin (riboflavin deficiency) in adults: 5-30 mg of riboflavin daily in divided doses.

For preventing migraine headaches: 400 mg of riboflavin (Vitamin B2) per day. It may take up to three months to get best results.

For preventing cataracts: approximately 2.6 mg of riboflavin (Vitamin B2).

Interactions

Drying medications (Anticholinergic drugs), Tricyclic antidepressants (used for depression), Phenobarbital, Probenecid.

Contraindications

Hypersensitivity to Riboflavin.

Side Effects

Riboflavin is generally safe for most individuals. In some cases, it may cause yellow-orange discoloration of urine. At high doses, it may lead to diarrhea, increased urination, and other mild adverse effects.

Pregnancy & Lactation

Riboflavin is considered safe for use during pregnancy and breastfeeding when taken within recommended doses.

Precautions & Warnings

Riboflavin is non-toxic. No specific warnings or special precautions have been established.

Therapeutic Class

Vitamin B preparations

Storage Conditions

Store in a cool, dry place. Protect from light.

Common Questions

What is Riboflavin for?

What does Riboflavin do?

What are the side effects of Riboflavin?

What happens if you take too much Riboflavin?

Is Riboflavin safe for pregnant women?

No available drugs found

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