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Myo-inositol

Generic Medicine
Indications

Inositol (Myo-inositol) is indicated in adults for the management of:

  • Polycystic ovary syndrome (PCOS)
  • Anovulation
  • Menstrual disorders such as amenorrhea
  • Hyperandrogenism-related conditions including hirsutism, alopecia, acanthosis nigricans, and acne
  • Ovarian hyperthecosis
  • Insulin resistance
  • Male infertility
Composition

Each film-coated tablet contains Inositol (Myo-inositol) USP 750 mg.

Pharmacology

Inositols are important molecules involved in female fertility and the maintenance of physiological pregnancy. Myo-inositol is the most abundant inositol isomer in the human body and is widely distributed in tissues such as the brain, blood, adipose tissue, kidneys, lungs, ovaries, and testes, where it participates in multiple cellular signaling pathways.

As a second messenger of gonadotropins and insulin, Myo-inositol plays a key role in normal oocyte development and embryogenesis. Clinical evidence suggests that Myo-inositol supplementation improves the chances of pregnancy and reduces adverse maternal and neonatal outcomes. It helps restore ovulation and normal menstrual cycles in infertile women, especially those with PCOS. It is also beneficial in assisted reproductive technology (ART) by improving oocyte and embryo quality. During pregnancy, it may reduce the risk of gestational diabetes mellitus (GDM), thereby lowering the risk of miscarriage and stillbirth. Additionally, it may help reduce neural tube defects (NTDs), particularly in folate-resistant cases.

Dosage Administration

Recommended dosage for lipid-lowering and improving conditions related to peripheral vascular insufficiency ranges from 1500 mg to 4000 mg daily, in divided dosages of two to three times daily with or without food for at least 3 months.

Use in children and adolescents: There is a lack of long-term safety data to support the safe use of Inositol (Myoinositol) in children and adolescents.

Interactions

Concomitant use of antidiabetic drugs with Inositol (Myo-inositol) may lead to an enhanced reduction in blood glucose compared to antidiabetic therapy alone.

Contraindications

Contraindicated in patients with known hypersensitivity to any component of this product.

Side Effects

Generally well tolerated at recommended doses. Mild gastrointestinal disturbances may occur at higher doses.

Pregnancy & Lactation

Inositol is possibly safe during pregnancy when taken orally. However, there is insufficient reliable data regarding its safety during breastfeeding.

Precautions & Warnings

Patients with diabetes should use this medication with caution due to its effect on blood glucose levels.

Overdose Effects

Inositol is generally safe and well tolerated when used in recommended doses.

Therapeutic Class

Nicotinic acid group / Oral nutritional preparation

Storage Conditions

Store in a cool, dry place away from light and moisture. Keep all medicines out of the reach of children.

Common Questions

What is Myo-inositol for?

What does Myo-inositol do?

What are the side effects of Myo-inositol?

What happens if you take too much Myo-inositol?

Can Myo-inositol be taken during pregnancy?

No available drugs found

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