Bisacodyl is indicated for:

• Treatment of constipation
• Bowel preparation before radiographic or endoscopic examination of the colon

Bisacodyl is a diphenolic compound with a chemical structure similar to phenolphthalein. It is commonly used as a laxative. It works by stimulating peristalsis in the colon and promoting the accumulation of water and electrolytes in the intestinal lumen. When it reaches the caecum, it triggers a response throughout the entire colon.

Constipation-

• Adult: 5-10 mg at night; occasionally necessary to increase to 15-20 mg;
• Child under 10 years: 5 mg.

Before radiological procedures and surgery-

• Adult: 10 mg orally at bed-time for 2 days before the examination.
• Child: half of the adult dose.

Bisacodyl should not be used in patients with ileus, intestinal obstruction, acute abdominal conditions such as appendicitis, inflammatory bowel diseases, or severe dehydration.

Bisacodyl is generally well tolerated when used at recommended doses. However, excessive use may lead to diarrhea and malabsorption. Prolonged or high-dose use can result in potassium depletion.

Bisacodyl should generally be avoided during pregnancy, especially in the first trimester. In breastfeeding women, it should be used with caution.

Excessive use of bisacodyl may cause fluid and electrolyte imbalance. Long-term use may lead to dependence on laxatives.

Stimulant purgatives

Store in a cool, dry place away from light.